Louisville, situated in the Commonwealth of Kentucky, boasts the distinction of being the most populous city in the state and the sixth-most populous city in the Southeastern United States. Additionally, it ranks as the 28th most populous city in the entire country. Louisville has served as the historical and nominal seat of Jefferson County since 2003, located on the border of Indiana.
The city owes its name to King Louis XVI of France and was established by George Rogers Clark in 1778. Louisville, being one of the oldest cities west of the Appalachians, flourished as a portage site due to the nearby Falls of Ohio, which was the sole major obstruction to river traffic between the upper Ohio River and the Gulf of Mexico.Notably, Louisville is renowned as the birthplace of iconic boxer Muhammad Ali, the acclaimed Kentucky Derby, Kentucky Fried Chicken, the University of Louisville and its Cardinals, Louisville Slugger baseball bats, and three of Kentucky's six Fortune 500 companies - Humana